Category Archives: Actualidad

AFM nanoindentation detection of the elastic modulus of tongue squamous carcinoma cells with different metastatic potentials – Uncorrected Proof

Abstract: Although significant advances have been made in understanding the molecular mechanisms that influence tongue squamous cell carcinoma (TSCC) metastasis, less is known about the association between the cellular elastic modulus and TSCC metastasis. Atomic force microscopy (AFM) nanoindentation via the rate-jump method was used to detect the… Continue reading

Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and a miniaturized micro-NMR system – Corrected Proof

Abstract: Circulating tumor cells (CTC) harvested from peripheral blood have received significant interest as sources for serial sampling to gauge treatment efficacy. Nanotechnology and microfluidic based approaches are emerging to facilitate such analyses. While of considerable clinical importance, there is little information on how similar or… Continue reading

Significant toxic role for single-walled carbon nanotubes during normal embryogenesis – Corrected Proof

Abstract: In order to investigate the effect of SWCNTs in the embryo, we examined the outcome of SWCNTs in avian embryo at an early stage of development. We found that SWCNTs-treatment inhibits the angiogenesis of the chorioallantoic membrane (CAM) and in the chicken embryo. Moreover, we showed that SWCNTs can harm the normal development of the… Continue reading

Guía OEPM: Patentes en nanotecnología

El número de solicitudes de patente europea para invenciones relacionadas con la nanotecnología se ha más que triplicado desde mediados de los años noventa.

Este folleto de la OEPM explica cómo iniciar la búsqueda de invenciones en el sector de la nanotecnología en bases de datos de patentes, y qué tener en cuenta si tiene previsto presentar una solicitud de patente de nanotecnología ante la Oficina Europea de Patentes.

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Dietary crystalline common-, micro-, nanoscale and emulsified nanoscale sitosterol reduce equally the cholesterol pool in guinea pigs, but varying nanosystems result in different sterol concentrations in serosal jejunum – Corrected Proof

Abstract: Due to hypocholesterolemic effects, sitosterol is used in functional foods and nanoscale dispersions. To investigate the influence of dietary sitosterol on sterol concentrations in Dunkin Hartley guinea pigs, seven groups consisting of eight animals each were fed either a basal diet (BD), a high-cholesterol diet (HC) or a… Continue reading

Single low-dose un-adjuvanted HBsAg nanoparticle vaccine elicits robust, durable immunity – Corrected Proof

Abstract: Chitosan nanoparticles were evaluated as a vaccine delivery system for hepatitis B surface antigen (HBsAg) in the absence of adjuvant. Nano-encapsulated HBsAg (HBsAg chitosan-NP) was endocytosed more rapidly and efficiently by dendritic cells compared to soluble HBsAg. FRET analysis demonstrated that intact nanoparticles were taken up by… Continue reading